Electron capture ionization of explosives with a microflow rate particle beam interface

被引：26

作者：

Cappiello, A ^{[1
]}

Famiglini, G ^{[1
]}

Lombardozzi, A ^{[1
]}

Massari, A ^{[1
]}

Vadala, GG ^{[1
]}

机构：

[1] SERV POLIZIA SCI,DIREZ CENT POLIZIA CRIMINALE,I-00144 ROME,ITALY

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 1996年 / 7卷 / 08期

关键词：

D O I：

10.1016/1044-0305(96)00015-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A method for the analysis of four widely used explosives based on reversed-phase liquid chromatography coupled to a quadrupole mass spectrometer is presented. A microflow rate particle beam interface was employed that offers simplified operation procedures and improved interfacing performance. A positive role played by the reduced size of the aerosol droplets generated by the microflow rate interface is outlined in this work. Greater vaporization efficiency and negligible thermal decomposition were observed for the selected compounds in the ion source of the mass spectrometer. Electron capture ionization allowed specific and sensitive determination of the analytes. Detection limits that ranged between 60 and 200 pg and had a signal-to-noise ratio of 5:1 were obtained in selected ion monitoring mode after column elution.

引用

页码：753 / 758

页数：6

共 15 条

[1] INVESTIGATION OF ENHANCED ION ABUNDANCES FROM A CARRIER PROCESS IN HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY PARTICLE BEAM MASS-SPECTROMETRY [J].

BELLAR, TA ;

BEHYMER, TD ;

BUDDE, WL .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1990, 1 (01) :92-98

[2] GENERATION OF SPIT-FLOW MICRO-GRADIENTS FOR CAPILLARY HPLC [J].

BERLONI, A ;

CAPPIELLO, A ;

FAMIGLINI, G ;

PALMA, P .

CHROMATOGRAPHIA, 1994, 39 (5-6) :279-284

[3] EVIDENCE FOR THERMAL-DECOMPOSITION CONTRIBUTIONS TO THE MASS-SPECTRA OF CHLORINATED PHENOXYACID HERBICIDES OBTAINED BY PARTICLE BEAM LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY [J].

BETOWSKI, LD ;

PACE, CM ;

ROBY, MR .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1992, 3 (08) :823-830

[4] NEW MATERIALS AND PACKING TECHNIQUES FOR MICRO-HPLC PACKED CAPILLARY COLUMNS [J].

CAPPIELLO, A ;

PALMA, P ;

MANGANI, F .

CHROMATOGRAPHIA, 1991, 32 (7-8) :389-391

[5] EVALUATION OR THE PERFORMANCE OF A MICROFLOW RATE LC/MS PARTICLE-BEAM INTERFACE [J].

CAPPIELLO, A ;

FAMIGLINI, G .

ANALYTICAL CHEMISTRY, 1994, 66 (22) :3970-3976

[6] MICRO FLOW-RATE PARTICLE BEAM INTERFACE FOR CAPILLARY LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY [J].

CAPPIELLO, A ;

BRUNER, F .

ANALYTICAL CHEMISTRY, 1993, 65 (09) :1281-1287

[7] ANALYSIS OF THERMALLY UNSTABLE COMPOUNDS BY A LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY PARTICLE-BEAM INTERFACE WITH A MODIFIED ION-SOURCE [J].

CAPPIELLO, A ;

FAMIGLINI, G .

ANALYTICAL CHEMISTRY, 1995, 67 (02) :412-419

[8] MASS-TRANSPORT AND CALIBRATION IN LIQUID-CHROMATOGRAPHY PARTICLE BEAM MASS-SPECTROMETRY [J].

HO, JS ;

BEHYMER, TD ;

BUDDE, WL ;

BELLAR, TA .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1992, 3 (06) :662-671

[9] ELECTRON-CAPTURE NEGATIVE-ION CHEMICAL IONIZATION MASS-SPECTROMETRY [J].

HUNT, DF ;

CROW, FW .

ANALYTICAL CHEMISTRY, 1978, 50 (13) :1781-1784

[10] ANALYSIS OF STYRENE OLIGOMERS BY PARTICLE BEAM LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY [J].

JONES, GG ;

PAULS, RE ;

WILLOUGHBY, RC .

ANALYTICAL CHEMISTRY, 1991, 63 (05) :460-463

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