Triggering of ovulation by a gonadotropin-releasing hormone (GnRH) agonist in patients pretreated with a GnRH antagonist

被引：68

作者：

Olivennes, F

Fanchin, R

Bouchard, P

Taieb, J

Frydman, R

机构：

[1] ANTOINE BECLERE HOSP,DEPT BIOCHEM,F-92140 CLAMART,FRANCE

[2] ST ANTOINE HOSP,DEPT ENDOCRINOL,PARIS,FRANCE

来源：

FERTILITY AND STERILITY | 1996年 / 66卷 / 01期

关键词：

GnRH agonist; GnRH antagonist; triggering of ovulation;

D O I：

10.1016/S0015-0282(16)58404-0

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To determine if GnRH-agonist (GnRH-a) could induce a LH surge in patients where a GnRH antagonist was used to prevent premature spontaneous LH surge. Design: Pilot study. Patients: Five patients treated with ovarian stimulation and IUI for idiopathic infertility. Main Outcome Measures: Luteinizing hormone, FSH, and P plasma levels. Results: A LH and FSH surge as well as a P rise were obtained in the five patients studied. Conclusion: A GnRH-a successfully can induce an LH surge after GnRH antagonist administration. The effect of the antagonist on the quality of the GnRH-a-induced LH surge as well as the oocyte quality remain to be evaluated.

引用

页码：151 / 153

页数：3