The common biology of cancer and ageing

被引：892

作者：

Finkel, Toren

Serrano, Manuel

Blasco, Maria A.

机构：

[1] NHLBI, Cardiol Branch, NIH, Bethesda, MD 20892 USA

[2] Spanish Natl Canc Res Ctr CNIO, Madrid 28029, Spain

来源：

NATURE | 2007年 / 448卷 / 7155期

关键词：

D O I：

10.1038/nature05985

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

At first glance, cancer and ageing would seem to be unlikely bedfellows. Yet the origins for this improbable union can actually be traced back to a sequence of tragic - and some say unethical - events that unfolded more than half a century ago. Here we review the series of key observations that has led to a complex but growing convergence between our understanding of the biology of ageing and the mechanisms that underlie cancer.

引用

页码：767 / 774

页数：8

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