Identification of the hypervirulent lineages of Neisseria meningitidis, the ST-8 and ST-11 complexes, by using monoclonal antibodies specific to NmeDI

被引：8

作者：

Claus, H ^{[1
]}

Weinand, H ^{[1
]}

Frosch, M ^{[1
]}

Vogel, U ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Hyg & Microbiol, D-97080 Wurzburg, Germany

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 08期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/JCM.41.8.3873-3876.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Most cases of serogroup C meningococcal disease are caused by the clonal lineages ST-8 and ST-11. The gene encoding the putative restriction-modification system NmeDI is specific to these lineages. We report here a monoclonal antibody directed against the NmeDI endonuclease as a tool for their rapid and specific identification.

引用

页码：3873 / 3876

页数：4

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