Should Oncologists Be Aware in Their Clinical Practice of KRAS Molecular Analysis?

被引：16

作者：

Santini, Daniele ^{[1
]}

Galluzzo, Sara ^{[1
]}

Gaeta, Laura ^{[1
]}

Zoccoli, Alice ^{[1
]}

Riva, Elisabetta ^{[1
]}

Ruzzo, Annamaria ^{[2
]}

Vincenzi, Bruno ^{[1
]}

Graziano, Francesco ^{[3
]}

Loupakis, Fotios ^{[4
]}

Falcone, Alfredo ^{[4
]}

Muda, Andrea Onetti ^{[1
]}

Tonini, Giuseppe ^{[1
]}

机构：

[1] Univ Campus Biomed, Rome, Italy

[2] Univ Urbino, Inst Biochem G Fornaini, I-61029 Urbino, Italy

[3] Azienda Osped Osped San Salvatore, Pesaro, Italy

[4] Azienda Osped Univ Pisana, Pisa, Italy

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2011年 / 29卷 / 08期

关键词：

MUTATIONS;

D O I：

10.1200/JCO.2010.32.7700

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：E206 / E207

页数：2

共 6 条

[1] American Society of Clinical Oncology Provisional Clinical Opinion: Testing for KRAS Gene Mutations in Patients With Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy [J].

Allegra, Carmen J. ;

Jessup, J. Milburn ;

Somerfield, Mark R. ;

Hamilton, Stanley R. ;

Hammond, Elizabeth H. ;

Hayes, Daniel F. ;

McAllister, Pamela K. ;

Morton, Roscoe F. ;

Schilsky, Richard L. .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (12) :2091-2096

[2]

FREEMAN DJ, 1998, SCIENCE, V281, P363

[3] KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer [J].

Lièvre, A ;

Bachet, JB ;

Le Corre, D ;

Boige, V ;

Landi, B ;

Emile, JF ;

Côté, JF ;

Tomasic, G ;

Penna, C ;

Ducreux, M ;

Rougier, P ;

Penault-Llorca, F ;

Laurent-Puig, P .

CANCER RESEARCH, 2006, 66 (08) :3992-3995

[4] KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab [J].

Lievre, Astrid ;

Bachet, Jean-Baptiste ;

Boige, Valerie ;

Cayre, Anne ;

Le Corre, Delphine ;

Buc, Emmanuel ;

Ychou, Marc ;

Bouche, Olivier ;

Landi, Bruno ;

Louvet, Christophe ;

Andre, Thierry ;

Bibeau, Frederic ;

Diebold, Marie-Daniele ;

Rougier, Philippe ;

Ducreux, Michel ;

Tomasic, Gorana ;

Emile, Jean-Francois ;

Penault-Llorca, Frederique ;

Laurent-Puig, Pierre .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (03) :374-379

[5] Comparison of Sanger Sequencing, Pyrosequencing, and Melting Curve Analysis for the Detection of KRAS Mutations Diagnostic and Clinical Implications [J].

Tsiatis, Athanasios C. ;

Norris-Kirby, Alexis ;

Rich, Roy G. ;

Hafez, Michael J. ;

Gocke, Christopher D. ;

Eshleman, James R. ;

Murphy, Kathleen M. .

JOURNAL OF MOLECULAR DIAGNOSTICS, 2010, 12 (04) :425-432

[6] KRAS Mutation Testing in Human Cancers: The Pathologist's Role in the Era of Personalized Medicine [J].

Wang, Hanlin L. ;

Lopategui, Jean ;

Amin, Mahul B. ;

Patterson, Scott D. .

ADVANCES IN ANATOMIC PATHOLOGY, 2010, 17 (01) :23-32

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