An efficient stereoselective synthesis of stypodiol and epistypodiol

被引：31

作者：

Abad, A ^{[1
]}

Agulló, C ^{[1
]}

Arnó, M ^{[1
]}

Cuñat, AC ^{[1
]}

Meseguer, B ^{[1
]}

Zaragozá, RJ ^{[1
]}

机构：

[1] Univ Valencia, Fac Quim, Dept Quim Organ, E-46100 Valencia, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 15期

关键词：

D O I：

10.1021/jo980311g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of stypodiol (1) and its epimer at C-14, epistypodiol (2), was accomplished starting from (S)-(+)-carvone (7). The synthesis of both epimeric compounds proceeds through common intermediates using an IMDA reaction, a sonochemical Barbier reaction, and an acid-catalyzed quinol-tertiary alcohol cyclization as key synthetic steps.

引用

页码：5100 / 5106

页数：7

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