Precision of INR measured with a patient operated whole blood coagulometer

被引:11
作者
Attermann, J
Andersen, NT
Korsgaard, H
Maegaard, M
Hasenkam, JM
机构
[1] Aarhus Univ, Dept Biostat, DK-8000 Aarhus C, Denmark
[2] Aarhus Univ Hosp, Skejby Sygehus, Dept Clin Biochem, DK-8000 Aarhus, Denmark
[3] Aarhus Univ Hosp, Skejby Sygehus, Dept Cardiothorac & Vasc Surg, DK-8000 Aarhus, Denmark
[4] Univ Aarhus, Inst Expt Clin Res, DK-8000 Aarhus C, Denmark
关键词
precision; international normalized ratio (INR); prothrombin time; self-care; whole blood coagulation time;
D O I
10.1016/S0049-3848(03)00294-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction: The objective of the present study was to evaluate the precision of a portable whole blood coagulometer (CoaguChek S) in the hands of self-managing patients on oral anticoagulant therapy (OAT). Materials and Methods: Fifteen patients on self-managed OAT performed measurements of INR by two types of portable whole blood coagulometers (CoaguChek and CoaguChek S) at home for 10 weeks. Results: The coefficient of variation (CV) of INRs determined at home by CoaguChek S by patients on self-managed OAT was 5.5% (95% confidence limits: 4.9%, 6.1%). The biological CV of INR within and between patients was 15.0% and 14.7%, respectively. Conclusion: The precision of CoaguChek S is satisfactory. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:65 / 68
页数:4
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