Pre-pro-somatostatin-III may have cortistatin-like functions in fish

被引:9
作者
Canosa, LF [1 ]
Peter, RE [1 ]
机构
[1] Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2E9, Canada
来源
TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY | 2005年 / 1040卷
关键词
SRIF; CTS; activity cycle; mRNA expression; brain; teleost fish;
D O I
10.1196/annals.1327.036
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This study analyzes daily changes in the expression of somatostatin precursors PSS-I and PSS-III (structurally related to cortistatin) in the goldfish brain. The results indicate that PSS-I expression correlates with the light cycle only in optic tectum-thalamus (OT-Tha). PSS-III expression correlates with the light cycle in telencephalon-preoptic area (Tel-POA) and OT-Tha. In Tel-POA, PSS-III reaches a minimum level at the beginning of the active phase and a maximum level late in this phase. These results suggest that PSS-I in OT-Tha and PSS-III in Tel-POA and OT-Tha could be involved in the control of the activity cycles in goldfish.
引用
收藏
页码:253 / 256
页数:4
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