Different prognostic importance of elevated troponin I after percutaneous coronary intervention in acute coronary syndrome and stable angina pectoris

被引：23

作者：

Gravning, Jorgen ^{[1
]}

Ueland, Thor ^{[2
]}

Morkrid, Lars ^{[3
,4
]}

Endresen, Knut ^{[5
,6
]}

Aaberge, Lars ^{[5
,6
]}

Kjekshus, John ^{[5
,6
]}

机构：

[1] Univ Oslo, Rikshosp, Univ Hosp, Inst Surg Res, N-0027 Oslo, Norway

[2] Univ Oslo, Rikshosp, Univ Hosp, Internal Med Res Inst, N-0027 Oslo, Norway

[3] Univ Oslo, Rikshosp, Univ Hosp, Dept Med Biochem, N-0027 Oslo, Norway

[4] Univ Oslo, Rikshosp, Univ Hosp, Inst Clin Biochem, N-0027 Oslo, Norway

[5] Univ Oslo, Rikshosp, Univ Hosp, Dept Cardiol, N-0027 Oslo, Norway

[6] Univ Oslo, Fac Med, N-0316 Oslo, Norway

来源：

SCANDINAVIAN CARDIOVASCULAR JOURNAL | 2008年 / 42卷 / 03期

关键词：

acute coronary syndrome; percutaneous coronary intervention; myocardial injury; prognosis;

D O I：

10.1080/14017430801932824

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives. To investigate the prognostic importance of cardiac troponin I (cTnI) elevation after percutaneous coronary intervention (PCI) in different clinical settings. Design. The study includes 238 patients presenting with acute coronary syndrome (ACS) and 194 patients with stable angina pectoris (SAP). The composite end point of death or hospitalization due to non-fatal myocardial infarction, repeated revascularization or unstable angina, was determined during one year of follow-up. Results. cTnI elevation after PCI was more frequent in ACS patients than SAP patients. ACS patients with cTnI elevation after PCI had significantly higher number of events than patients with unchanged cTnI status after PCI. SAP patients had generally lower event rate than ACS patients. The event rate was also significantly higher among ACS patients than SAP patients at comparable degrees of cTnI elevation after PCI There was no difference in events among SAP patients with or without cTnI elevation after PCI. Conclusion. cTnI elevation after PCI predicts adverse outcome after one year in patients with ACS, but not in patients with SAP.

引用

页码：214 / 221

页数：8

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