The potential role of chitin in allergic reactions

被引：30

作者：

Burton, Oliver T. ^{[1
]}

Zaccone, Paola ^{[1
]}

机构：

[1] Univ Cambridge, Dept Pathol, Cambridge CB2 1QP, England

来源：

TRENDS IN IMMUNOLOGY | 2007年 / 28卷 / 10期

关键词：

D O I：

10.1016/j.it.2007.08.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Allergy, a potentially life-threatening condition, has at its heart an overly zealous T-helper type 2 response to environmental antigens. We are constantly flooded by potential allergens, both airborne and ingested. Although innocuous to some, common antigens can cause serious allergic reactions in susceptible individuals. Chitin, a polymerized sugar and fundamental component of arthropods and fungi, is not commonly deemed a potential allergen but can cause sensitization through frequent exposure. A recent intriguing study has highlighted the role of chitin in allergic reactions.

引用

页码：419 / 422

页数：4

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