Preparation of 4-substituted 3-amino-2-chloropyridines, synthesis of a Nevirapine analogue

被引：11

作者：

Bakke, JM ^{[1
]}

Riha, J ^{[1
]}

机构：

[1] Norwegian Univ Sci & Technol, Dept Chem, N-7491 Trondheim, Norway

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2001年 / 38卷 / 01期

关键词：

D O I：

10.1002/jhet.5570380114

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for preparing 3-amino-2-chloropyridines with a substituent (methyl, phenyl, carboxamide, methoxycarbonyl, acetyl, benzoyl and cyano) at the 4-position has been developed. An isoquinoline analogue of the reverse transcriptase inhibitor Nevirapine has been synthesized from the 4-amino-3-chloroisoquinoline.

引用

页码：99 / 104

页数：6

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