A convergent synthesis of polysubstituted aromatic nitriles via palladium-catalyzed C-H functionalization

被引：183

作者：

Mariampillai, Brian ^{[1
]}

Alliot, Julien ^{[1
]}

Li, Mengzhou ^{[1
]}

Lautens, Mark ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Davenport Res Lab, Toronto, ON M5S 3H6, Canada

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 49期

关键词：

D O I：

10.1021/ja075599i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium-catalyzed C-H functionalization reaction for the synthesis of highly substituted aromatic nitriles is reported. The modularity of the reaction is demonstrated by the broad range of aryl iodides which can be coupled with metal cyanides and alkyl halides or aryl bromides.

引用

页码：15372 / 15379

页数：8

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