Immunology 102 at poxvirus U: Avoiding apoptosis

被引：28

作者：

Shisler, JL ^{[1
]}

Moss, B ^{[1
]}

机构：

[1] NIAID, Viral Dis Lab, NIH, Bethesda, MD 20892 USA

来源：

SEMINARS IN IMMUNOLOGY | 2001年 / 13卷 / 01期

关键词：

apoptosis; cell death; poxvirus; caspase;

D O I：

10.1006/smim.2000.0297

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Poxviruses are large complex viruses that replicate in the cytoplasm of cells without integrating their DNA into the host genome or undergoing a latent intracellular stage. In addition to viral enzymes for DNA and RNA synthesis, poxviruses encode many proteins that modulate host responses. These include inhibitors of apoptosis induced by ligand binding to cell surface receptors, peroxides, ultraviolet light, DNA damaging agents and other cell signaling pathways.

引用

收藏

页码：67 / 72

页数：6

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