Neuronal variability: Noise or part of the signal?

被引：459

作者：

Stein, RB ^{[1
]}

Gossen, ER

Jones, KE

机构：

[1] Univ Alberta, Dept Physiol, Edmonton, AB T6G 2S2, Canada

[2] Univ Alberta, Ctr Neurosci, Edmonton, AB T6G 2S2, Canada

[3] Univ Alberta, Dept Biomed Engn, Edmonton, AB T6G 2S2, Canada

来源：

NATURE REVIEWS NEUROSCIENCE | 2005年 / 6卷 / 05期

关键词：

D O I：

10.1038/nrn1668

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Sensory, motor and cortical neurons fire impulses or spikes at a regular, but slowly declining, rate in response to a constant current stimulus. Yet, the intervals between spikes often vary randomly during behaviour. Is this variation an unavoidable effect of generating spikes by sensory or synaptic processes ('neural noise') or is it an important part of the 'signal' that is transmitted to other neurons? Here, we mainly discuss this question in relation to sensory and motor processes, as the signals are best identified in such systems, although we also touch on central processes.

引用

页码：389 / 397

页数：9

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