Biomonitoring the genotoxicity of environmental factors with transgenic plants

被引：32

作者：

Kovalchuk, I ^{[1
]}

Kovalchuk, O ^{[1
]}

Hohn, B ^{[1
]}

机构：

[1] Friedrich Miescher Inst, CH-4002 Basel, Switzerland

来源：

TRENDS IN PLANT SCIENCE | 2001年 / 6卷 / 07期

关键词：

D O I：

10.1016/S1360-1385(01)01985-9

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

All organisms must react to constantly changing surroundings. Environmental factors are thus powerful forces continuously shaping the genomes of all species. Induced genetic changes can be followed using a biomonitor - a living organism that reacts to a given compound in the environment. A vital but challenging task is identifying organisms with which to study the influence of changing environmental conditions. Plants are especially valuable biomonitors. Here, we describe the use of transgenic plant systems to evaluate the genotoxicity of chemical and radiological compounds. We evaluate the potential of further transgene-based systems for studying somatic and germline mutations.

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页码：306 / 310

页数：5

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