Conflicting evidence on the frequency of ESR1 amplification in breast cancer

被引：21

作者：

Albertson, Donna G. ^{[1
,2
]}

机构：

[1] Univ Calif San Francisco, Canc Res Inst, Dept Lab Med, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

来源：

NATURE GENETICS | 2008年 / 40卷 / 07期

关键词：

D O I：

10.1038/ng0708-821

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

An earlier report of high-frequency ESR1 amplification in breast cancer is now challenged by correspondence from four groups. This discussion of whether or not there is something 'FISHy' about ESR1 amplification highlights the difficulty of validating such observations, leaving the frequency and clinical significance of ESR1 amplification in breast cancer an open question.

引用

页码：821 / 822

页数：3

共 13 条

[1] Gene amplification in cancer [J].

Albertson, Donna G. .

TRENDS IN GENETICS, 2006, 22 (08) :447-455

[2] ESR1 gene amplification in breast cancer: a common phenomenon? [J].

Lindsay A Brown ;

Jeremy Hoog ;

Suet-Feung Chin ;

Yu Tao ;

Abd Alnaser Zayed ;

Koei Chin ;

Andrew E Teschendorff ;

John F Quackenbush ;

John C Marioni ;

Samuel Leung ;

Charles M Perou ;

Torsten O Neilsen ;

Matthew Ellis ;

Joe W Gray ;

Philip S Bernard ;

David G Huntsman ;

Carlos Caldas .

Nature Genetics, 2008, 40 (7) :806-807

[3]

EJLERTSEN B, 2007, SAN ANT BREAST CANC

[4] Breast tumor copy number aberration phenotypes and genomic instability [J].

Fridlyand, J ;

Snijders, AM ;

Ylstra, B ;

Li, H ;

Olshen, A ;

Segraves, R ;

Dairkee, S ;

Tokuyasu, T ;

Ljung, BM ;

Jain, AN ;

McLennan, J ;

Ziegler, J ;

Chin, K ;

Devries, S ;

Feiler, H ;

Gray, JW ;

Waldman, F ;

Pinkel, D ;

Albertson, DG .

BMC CANCER, 2006, 6 (1)

[5] ESR1 gene amplification in breast cancer:: a common phenomenon?: Reply [J].

Holst, Frederik ;

Stahl, Phillip ;

Hellwinkel, Olaf ;

Dancau, Ana-Maria ;

Krohn, Antje ;

Wuth, Laura ;

Heupel, Christian ;

Lebeau, Annette ;

Terracciano, Luigi ;

Al-Kuraya, Khawla ;

Jaenicke, Fritz ;

Sauter, Guido ;

Simon, Ronald .

NATURE GENETICS, 2008, 40 (07) :810-812

[6] Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer [J].

Holst, Frederik ;

Stahl, Phillip R. ;

Ruiz, Christian ;

Hellwinkel, Olaf ;

Jehan, Zeenath ;

Wendland, Marc ;

Lebeau, Annette ;

Terracciano, Luigi ;

Al-Kuraya, Khawla ;

Jaenicke, Fritz ;

Sauter, Guido ;

Simon, Ronald .

NATURE GENETICS, 2007, 39 (05) :655-660

[7]

Horlings HM, 2008, NAT GENET, V40, P807, DOI 10.1038/ng0708-807

[8] ESTROGEN-RECEPTOR GENE AMPLIFICATION IS FOUND IN SOME ESTROGEN RECEPTOR-POSITIVE HUMAN BREAST-TUMORS [J].

NEMBROT, M ;

QUINTANA, B ;

MORDOH, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1990, 166 (02) :601-607

[9] Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors [J].

Pollack, JR ;

Sorlie, T ;

Perou, CM ;

Rees, CA ;

Jeffrey, SS ;

Lonning, PE ;

Tibshirani, R ;

Botstein, D ;

Borresen-Dale, AL ;

Brown, PO .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (20) :12963-12968

[10] Evaluation of HER-2/neu gene amplification and overexpression:: Comparison of frequently used assay methods in a molecularly characterized cohort of breast cancer specimens [J].

Press, MF ;

Slamon, DJ ;

Flom, KJ ;

Park, J ;

Zhou, JY ;

Bernstein, L .

JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (14) :3095-3105

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