Production of 64Cu on the Sherbrooke TR-PET cyclotron

被引:28
作者
Zeisler, SK
Pavan, RA
Orzechowski, J
Langlois, R
Rodrigue, S
van Lier, JE
机构
[1] TRIUMF, Appl Technol Grp, Vancouver, BC V6T 2A3, Canada
[2] Univ Sherbrooke, Fac Med, Sherbrooke PET Ctr, Sherbrooke, PQ J1H 5N5, Canada
关键词
Physical Chemistry; Nickel; Inorganic Chemistry; Anion Exchange; Rhodium;
D O I
10.1023/A:1024782318219
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
At energies less than or equal to15 MeV, Cu-64 is most readily produced using the Ni-64(p,n)Cu-64 reaction. Space restrictions in the TR-PET target selector required a target system of compact design that would still allow the quick and easy removal of the irradiated target. The target consists of a Ni-64-plated rhodium disc held in place by a threaded cooling assembly. For removal, the cooling block is rotated slightly, allowing the disc to fall into a shielding container. The nickel is dissolved and the Cu-64 separated by anion exchange or electrochemical deposition. Yields of up to 330 mCi of radiochemically pure Cu-64 have been obtained.
引用
收藏
页码:175 / 177
页数:3
相关论文
共 2 条
[1]   Efficient production of high specific activity Cu-64 using a biomedical cyclotron [J].
McCarthy, DW ;
Shefer, RE ;
Klinkowstein, RE ;
Bass, LA ;
Margeneau, WH ;
Cutler, CS ;
Anderson, CJ ;
Welch, MJ .
NUCLEAR MEDICINE AND BIOLOGY, 1997, 24 (01) :35-43
[2]  
MIRZADEH S, 1992, RADIOCHIM ACTA, V57, P193