Lanthanide binuclear macrocyclic complexes as synthetic enzymes for the cleavage of DNA

被引：21

作者：

Zhu, B

Zhao, DQ

Ni, JZ

Ying, D

Huang, BQ

Wang, ZL

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, Lab Rare Earth Chem & Phys, Changchun 130022, Peoples R China

[2] NE Normal Univ, Inst Cytol & Genet, Changchun 130024, Peoples R China

[3] Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1998年 / 135卷 / 01期

基金：

中国国家自然科学基金;

关键词：

DNA cleavage; supramolecular chemistry; lanthanide complexes;

D O I：

10.1016/S1381-1169(98)00175-7

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Lanthanide binuclear complexes can accelerate the cleavage of pUC19 plasmid DNA, yielding predominantly linear form. The saturation kinetics of the cleavage of pUC19 was studied. The observed rates with lanthanide binuclear complexes showed the expected increase with the catalyst concentration. The rate of cleavage is greater than that of lanthanide ions alone. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：107 / 110

页数：4

共 18 条

[1] METALS AND DNA - MOLECULAR LEFT-HANDED COMPLEMENTS [J].