Hepatoprotective triterpenes from Sedum sarmentosum

被引：47

作者：

He, AM ^{[1
]}

Wang, MS

Hao, HY

Zhang, DC

Lee, KH

机构：

[1] Shanghai Med Univ, Sch Pharm, Dept Chem Nat Drugs, Shanghai 200032, Peoples R China

[2] Shanghai Med Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 200032, Peoples R China

[3] China Pharmaceut Univ, Dept Phytochem, Nanjing 210009, Peoples R China

[4] Univ N Carolina, Sch Pharm, Div Med Chem & Nat Prod, Nat Prod Lab, Chapel Hill, NC 27599 USA

来源：

PHYTOCHEMISTRY | 1998年 / 49卷 / 08期

关键词：

Sedum sarmentosum; Crassulaceae; triterpene; sarmentolin; hepatoprotective activity;

D O I：

10.1016/S0031-9422(98)00434-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The known delta-amyrone, 3-epi-delta-amyrin, delta-amyrin as well as anew hydroperoxy triterpene, 18 beta-hydroperoxy-olean-12-en-3-one (named sarmentolin) were isolated as hepatoprotective agents from Sedum sarmentosum. Their structures were elucidated by spectral analysis and chemical reactions. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2607 / 2610

页数：4

共 19 条

[1] MASS SPECTROMETRY IN STRUCTURAL AND STEREOCHEMICAL PROBLEMS .32. PENTACYCLIC TRITERPENES [J].

BUDZIKIEWICZ, H ;

WILSON, JM ;

DJERASSI, C .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1963, 85 (22) :3688-&

[2] ISOLATION AND RELAY SYNTHESIS OF 11-ALPHA-HYDROPEROXY DIACETYL HEDERAGENIN, A NOVEL TRITERPENOID DERIVATIVE FROM SERJANIA-TRIQUETRA (SAPINDACEAE) - BIOGENETIC IMPLICATIONS [J].

CHAVEZ, MI ;

DELGADO, G .

TETRAHEDRON, 1994, 50 (13) :3869-3878

[3]

DHAVEJI K, 1984, J INDIAN CHEM SOC, V61, P1032

[4]

DODDRELL DM, 1974, TETRAHEDRON LETT, P2381

[5]

FANG SD, 1982, ACTA CHIM SINICA, V40, P273

[6]

FANG SD, 1979, KEXUE TONGBAO, P431

[7]

He A., 1997, ZHONGCAOYAO, V28, P517

[8]

He A., 1997, J CHINA PHARM UNIV, V28, P271

[9]

*JIANG SU NEW MED, 1993, ENCY CHIN MAT MED, P608

[10] EPICUTICULAR WAX CONSTITUENTS OF NORTH-AMERICAN AND EUROPEAN EUPHORBIA-ESULA BIOTYPES [J].

MANNERS, GD ;

DAVIS, DG .

PHYTOCHEMISTRY, 1984, 23 (05) :1059-1062

← 1 2 →