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Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons

被引：200
作者：
Pellerin, L [1 ]
Magistretti, PJ [1 ]
机构：
[1] Univ Lausanne, Inst Physiol, CH-1005 Lausanne, Switzerland
来源：
NEUROSCIENTIST | 2004年 / 10卷 / 01期
关键词：
glucose; lactate; monocarboxylate transporters; aerobic glycolysis; brain energy metabolism;
D O I：
10.1177/1073858403260159
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Classical neuroenergetics states that glucose is the exclusive energy substrate of brain cells and its full oxidation provides all the necessary energy to support brain function. Recent data have revealed a more intricate picture in which astrocytes play a key role in supplying lactate as an additional energy substrate in register with glutamatergic activity.
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页码：53 / 62
页数：10
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