New and easy route to primary cyclopropylamines from nitriles

被引：78

作者：

Bertus, P

Szymoniak, J ^{[1
]}

机构：

[1] CNRS, UMR 6519, F-51687 Reims 2, France

[2] Univ Reims, F-51687 Reims 2, France

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 18期

关键词：

D O I：

10.1039/b105293b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Starting from readily available substrates, we have developed a new synthesis of primary cyclopropylamines. The reaction involves a cooperative Ti(II)- and Lewis acid-mediated coupling of alkanenitriles with Grignard reagents.

引用

页码：1792 / 1793

页数：2

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