Estimating the size of the olfactory repertoire

被引:6
作者
Carmel, L [1 ]
Harel, D
Lancet, D
机构
[1] Weizmann Inst Sci, Dept Appl Math & Comp Sci, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel
关键词
D O I
10.1006/bulm.2001.0259
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The concept of shape space, which has been successfully implemented in immunology, is used here to construct a model for the discrimination power of the olfactory system. Using reasonable assumptions on the behaviour of the biological system, we are able to estimate the number of distinct olfactory receptor types. Our estimated value of around 1000 receptor types is in good agreement with experimental data. (C) 2001 Society for Mathematical Biology.
引用
收藏
页码:1063 / 1078
页数:16
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