Correlation of reactive oxygen species levels with the fertilization rate after in vitro fertilization: a qualified meta-analysis

被引：73

作者：

Agarwal, A

Allamaneni, SSR

Nallella, KP

George, AT

Mascha, E

机构：

[1] Cleveland Clin Fdn, Ctr Res Reprod, Glickman Urol Inst, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Ctr Adv Res Human Reprod Infertil & Sexual Funct, Glickman Urol Inst, Cleveland, OH USA

[3] Cleveland Clin Fdn, Dept Obstet & Gynecol, Cleveland, OH USA

[4] Cleveland Clin Fdn, Dept Biostat & Epidemiol, Cleveland, OH 44195 USA

来源：

FERTILITY AND STERILITY | 2005年 / 84卷 / 01期

关键词：

D O I：

10.1016/j.fertnstert.2004.12.057

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

Our meta-analysis analyzed the relationship between levels of reactive oxygen species (ROS) and fertilization rate after in vitro fertilization (IVF), and showed a statistically significant correlation between the ROS levels and the lVF fertilization rate (estimated overall correlation -0.374 [95% Cl, -0.520, -0.205]). We conclude that ROS has a statistically significant effect on the fertilization rate after lVF, and that the measurement of ROS levels in semen specimens before lVF may be useful in predicting the lVF outcome and in counseling patients. (c) 2005 by American Society for Reproductive Medicine.

引用

页码：228 / 231

页数：4

共 31 条

[1]

Role of reactive oxygen species in the pathophysiology of human reproduction [J].