Role of reactive oxygen species in cell signalling pathways

被引：494

作者：

Hancock, JT ^{[1
]}

Desikan, R ^{[1
]}

Neill, SJ ^{[1
]}

机构：

[1] Univ W England, Fac Sci Appl, Free Rad Res Grp, Bristol BS16 1QY, Avon, England

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2001年 / 29卷

关键词：

gene expression; hydrogen peroxide; MAP kinases; NADPH oxidase; signal transduction;

D O I：

10.1042/0300-5127:0290345

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Reactive oxygen species (ROS) were originally thought to only be released by phagocytic cells during their role in host defence. It is now clear that ROS have a cell signalling role in many biological systems, both in animals and in plants. ROS induce programmed cell death or necrosis, induce or suppress the expression of many genes, and activate cell signalling cascades, such as those involving mitogen-activated protein kinases.

引用

页码：345 / 350

页数：6

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