Subpicosecond conformational dynamics of small peptides probed by two-dimensional vibrational spectroscopy

被引：177

作者：

Woutersen, S

Mu, YG

Stock, G

Hamm, P

机构：

[1] Max Born Inst Nonlinear Opt & Short Pulse Spect, D-12489 Berlin, Germany

[2] Univ Frankfurt, Inst Phys & Theoret Chem, D-60439 Frankfurt, Germany

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2001年 / 98卷 / 20期

关键词：

D O I：

10.1073/pnas.201169498

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The observation of subpicosecond fluctuations in the conformation of a small peptide in water is demonstrated. We use an experimental method that is specifically sensitive to conformational dynamics taking place on an ultrafast time scale. Complementary molecular-dynamics simulations confirm that the conformational fluctuations exhibit a subpicosecond component, the time scale and amplitude of which agree well with those derived from the experiment.

引用

页码：11254 / 11258

页数：5

共 26 条

[1] Ultrafast energy transfer in LHC-II revealed by three-pulse photon echo peak shift measurements
Agarwal, R
Krueger, BP
Scholes, GD
Yang, M
Yom, J
Mets, L
Fleming, GR
[J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2000, 104 (13): : 2908 - 2918
[2] Two-dimensional infrared spectroscopy of peptides by phase-controlled femtosecond vibrational photon echoes
Asplund, MC
Zanni, MT
Hochstrasser, RM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (15) : 8219 - 8224
[3] MOLECULAR-DYNAMICS WITH COUPLING TO AN EXTERNAL BATH
BERENDSEN, HJC
POSTMA, JPM
VANGUNSTEREN, WF
DINOLA, A
HAAK, JR
[J]. JOURNAL OF CHEMICAL PHYSICS, 1984, 81 (08) : 3684 - 3690
[4] Chemical physics of protein folding
Brooks, CL
Gruebele, M
Onuchic, JN
Wolynes, PG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (19) : 11037 - 11038
[5] FUNNELS, PATHWAYS, AND THE ENERGY LANDSCAPE OF PROTEIN-FOLDING - A SYNTHESIS
BRYNGELSON, JD
ONUCHIC, JN
SOCCI, ND
WOLYNES, PG
[J]. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1995, 21 (03) : 167 - 195
[6] Quantum dynamics and vibrational relaxation
Egorov, SA
Everitt, KF
Skinner, JL
[J]. JOURNAL OF PHYSICAL CHEMISTRY A, 1999, 103 (47) : 9494 - 9499
[7] Two-dimensional electronic correlation and relaxation spectra: Theory and model calculations
Faeder, SMG
Jonas, DM
[J]. JOURNAL OF PHYSICAL CHEMISTRY A, 1999, 103 (49) : 10489 - 10505
[8] Frauenfelder H, 2000, ANN PHYS-BERLIN, V9, P655, DOI 10.1002/1521-3889(200010)9:9/10<655::AID-ANDP655>3.0.CO
[9] 2-Z
[10] Noise suppression in femtosecond mid-infrared light sources
Hamm, P
Kaindl, RA
Stenger, J
[J]. OPTICS LETTERS, 2000, 25 (24) : 1798 - 1800

← 1 2 3 →