Placebo responses and placebo effects in functional bowel disorders

被引：33

作者：

Enck, Paul ^{[1
]}

Horing, Bjoern ^{[1
]}

Weimer, Katja ^{[1
]}

Klosterhalfen, Sibylle ^{[1
]}

机构：

[1] Univ Tubingen Hosp, Dept Psychosomat Med, Tubingen, Germany

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 2012年 / 24卷 / 01期

关键词：

clinical trials; functional bowel disorders; placebo response; RANDOMIZED CLINICAL-TRIALS; COMPARING PLACEBO; INFORMED-CONSENT; DOUBLE-BLIND; METAANALYSIS; DYSPEPSIA; EFFICACY; SCHIZOPHRENIA; EXPECTATION; PREDICTORS;

D O I：

10.1097/MEG.0b013e32834bb951

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

The nature and determinants of the placebo response are widely unknown, as are the underlying psychological and biological mechanisms. Placebo response rates in functional bowel disorders (functional dyspepsia, irritable bowel syndrome) trials are similar to those in nonintestinal pain conditions and are comparable with other organic gastrointestinal diseases (duodenal ulcer, inflammatory bowel diseases). In this narrative review, different methodologies (meta-analyses, reanalyses, and experimental setups) are discussed that have been applied to the study of the placebo response in functional dyspepsia and the irritable bowel syndrome. Eur J Gastroenterol Hepatol 24: 1-8 (C) 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.

引用

页码：1 / 8

页数：8

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