Chemoembolization of hepatic metastases from ocular melanoma: Assessment of response with contrast-enhanced and diffusion-weighted MRI

被引：26

作者：

Buijs, Manon ^{[1
]}

Vossen, Josephina A. ^{[1
]}

Hong, Kelvin ^{[1
]}

Georgiades, Christos S. ^{[1
]}

Geschwind, Jean-Francois H. ^{[1
]}

Kamel, Ihab R. ^{[1
]}

机构：

[1] Johns Hopkins Univ Hosp, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA

来源：

AMERICAN JOURNAL OF ROENTGENOLOGY | 2008年 / 191卷 / 01期

关键词：

diffusion-weighted MRI; hepatic metastases; liver; metastatic ocular melanoma; perfusion MRI; transarterial chemoembolization; treatment response;

D O I：

10.2214/AJR.07.2467

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];

摘要：

OBJECTIVE. The purpose of this study was to assess the utility of assessment of tumor size and enhancement with diffusion-weighted and conventional MRI in the evaluation of response to transarterial chemoembolization therapy for metastatic ocular melanoma. CONCLUSION. In patients with ocular melanoma and liver metastasis treated with transarterial chemoembolization, functional MRI showed significant changes in the lesions. These changes included a decrease in tumor enhancement and an increase in the apparent diffusion coefficient of the tumor, suggesting increasing tumor necrosis and cell death.

引用

页码：285 / 289

页数：5

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