N6-arylation of 2′-deoxyadenosine via copper-catalyzed direct coupling with aryl halides

被引：26

作者：

Ran, CZ ^{[1
]}

Dai, Q ^{[1
]}

Harvey, RG ^{[1
]}

机构：

[1] Univ Chicago, Ben May Inst Canc Res, Chicago, IL 60637 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 09期

关键词：

D O I：

10.1021/jo040284w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general method for efficient N-6-arylation of 2 '-deoxyadenosine via copper-catalyzed direct coupling with aryl iodides and bromides is described. The method is useful for aryl halides with either electron-donating or electron-withdrawing groups.

引用

页码：3724 / 3726

页数：3

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