Efficacy of regulatory T-cell immunotherapy: are inflammatory cytokines key determinants?

被引：11

作者：

Bayry, Jagadeesh ^{[1
,2
]}

Lacroix-Desmazes, Sebastien ^{[1
,2
]}

Dasgupta, Suryasarathi ^{[1
,2
]}

Kazatchkine, Michel D. ^{[1
,2
]}

Kaveri, Srini V. ^{[1
,2
]}

机构：

[1] Univ Paris 06, Ctr Rech Cordeliers, INSERM, UMR S872, F-75006 Paris, France

[2] Univ Paris 05, INSERM, U872, F-75006 Paris, France

来源：

NATURE REVIEWS IMMUNOLOGY | 2008年 / 8卷 / 01期

关键词：

D O I：

10.1038/nri2138-c1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1 / 2

页数：2

共 15 条

[1] CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis [J].

Bardos, T ;

Czipri, M ;

Vermes, C ;

Finnegan, A ;

Mikecz, K ;

Zhang, J .

ARTHRITIS RESEARCH & THERAPY, 2003, 5 (02) :R106-R113

[2] Rescuing CD4+CD25+ regulatory T-cell functions in rheumatoid arthritis by cytokine-targeted monoclonal antibody therapy [J].

Bayry, Jagadeesh ;

Siberil, Sophie ;

Triebel, Frederic ;

Tough, David F. ;

Kaveri, Srin V. .

DRUG DISCOVERY TODAY, 2007, 12 (13-14) :548-552

[3] Monoclonal antibody and intravenous immunoglobulin therapy for rheumatic diseases: rationale and mechanisms of action [J].

Bayry, Jagadeesh ;

Lacroix-Desmazes, Sebastien ;

Kazatchkine, Michel D. ;

Kaveri, Srini V. .

NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2007, 3 (05) :262-272

[4] Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells [J].

Bayry, Jagadeesh ;

Triebel, Frederic ;

Kaveri, Srini V. ;

Tough, David F. .

JOURNAL OF IMMUNOLOGY, 2007, 178 (07) :4184-4193

[5] Long-term treatment of rheumatoid arthritis with tumour necrosis factor α blockade:: outcome of ceasing and restarting biologicals [J].

Buch, MH ;

Marzo-Ortega, H ;

Bingham, SJ ;

Emery, P .

RHEUMATOLOGY, 2004, 43 (02) :243-244

[6] Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy [J].

Ehrenstein, MR ;

Evans, JG ;

Singh, A ;

Moore, S ;

Warnes, G ;

Isenberg, DA ;

Mauri, C .

JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 200 (03) :277-285

[7] The role of regulatory T cells in antigen-induced arthritis:: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells [J].

Frey, O ;

Petrow, PK ;

Gajda, M ;

Siegmund, K ;

Huehn, J ;

Scheffold, A ;

Hamann, A ;

Radbruch, A ;

Bräuer, R .

ARTHRITIS RESEARCH & THERAPY, 2005, 7 (02) :R291-R301

[8] Human CD4+CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation [J].

Houot, Roch ;

Perrot, Ivan ;

Garcia, Eric ;

Durand, Isabelle ;

Lebecque, Serge .

JOURNAL OF IMMUNOLOGY, 2006, 176 (09) :5293-5298

[9] Regulatory T cells in rheumatoid arthritis [J].

Leipe, J ;

Skapenko, A ;

Lipsky, PE ;

Schulze-Koops, H .

ARTHRITIS RESEARCH & THERAPY, 2005, 7 (03) :93-99

[10] Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes [J].

Lindley, S ;

Dayan, CM ;

Bishop, A ;

Roep, BO ;

Peakman, M ;

Tree, TIM .

DIABETES, 2005, 54 (01) :92-99

← 1 2 →