Fluorescence detection of guanine-adenine transition by a hydrogen bond forming small compound

被引:53
作者
Yoshimoto, K [1 ]
Xu, CY [1 ]
Nishizawa, S [1 ]
Haga, T [1 ]
Satake, H [1 ]
Teramae, NE [1 ]
机构
[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Aoba Ku, Sendai, Miyagi 9808578, Japan
关键词
D O I
10.1039/b309229a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In combination with abasic site-containing oligodeoxynucleotides, 2-amino-4-oxopteridine (pterin) can selectively recognize guanine base over other nucleobases accompanied by fluorescence quenching, which allows clear detection of a guanine-adenine transition with the naked eye.
引用
收藏
页码:2960 / 2961
页数:2
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