Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study

被引：81

作者：

Ballantyne, C. M. ^{[1
,2
]}

Hoogeveen, R. C. ^{[1
,2
]}

McNeill, A. M. ^{[3
,4
]}

Heiss, G. ^{[4
]}

Schmidt, M. I. ^{[4
,5
]}

Duncan, B. B. ^{[4
,5
]}

Pankow, J. S. ^{[6
]}

机构：

[1] Baylor Coll Med, Dept Med, Sect Atherosclerosis & Vasc Med, Houston, TX 77030 USA

[2] Methodist DeBakey Heart Ctr, Ctr Cardiovasc Dis Prevent, Houston, TX 77030 USA

[3] Merck Res Labs, Dept Epidemiol, N Wales, PA USA

[4] Univ N Carolina, Sch Publ Hlth, Dept Epidemiol, Chapel Hill, NC USA

[5] Univ Fed Rio Grande do Sul, Sch Med, Grad Studies Program Epidemiol, Porto Alegre, RS, Brazil

[6] Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA

来源：

INTERNATIONAL JOURNAL OF OBESITY | 2008年 / 32卷 / Suppl 2期

关键词：

metabolic syndrome; coronary heart disease; cardiovascular disease; diabetes; risk factors;

D O I：

10.1038/ijo.2008.31

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Objective: The metabolic syndrome is associated with increased risk for cardiovascular disease and diabetes. Several analyses from the Atherosclerosis Risk in Communities (ARIC) study have been performed to examine the role of the metabolic syndrome and its components in predicting risk for cardiovascular disease and diabetes. Design and subjects: The large, biracial, population-based ARIC study enrolled 15 792 middle-aged Americans in four communities in the United States and has followed them for the development of cardiovascular disease and diabetes. Measurements: Outcome parameters included prevalence of the metabolic syndrome and its individual components, carotid intima-media thickness, incident coronary heart disease, incident ischemic stroke and incident diabetes. Results and conclusion: Several analyses from the ARIC study have shown that the metabolic syndrome, as well as individual metabolic syndrome components, is predictive of the prevalence and incidence of coronary heart disease, ischemic stroke, carotid artery disease and diabetes.

引用

页码：S21 / S24

页数：4

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