Role of homeobox genes in the patterning, specification, and differentiation of ectodermal appendages in mammals

被引：87

作者：

Duverger, Olivier ^{[1
]}

Morasso, Maria I. ^{[1
]}

机构：

[1] NIAMSD, Dev Skin Biol Unit, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 2008年 / 216卷 / 02期

关键词：

D O I：

10.1002/jcp.21491

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Homeobox genes are an evolutionarily conserved class of transcription factors that are key regulators during developmental processes such as regional specification, patterning, and differentiation. In this review, we summarize the expression pattern, loss- and/or gain-of-function mouse models, and naturally occurring mouse and human mutations of known homeobox genes required for the development of ectodermal appendages.

引用

页码：337 / 346

页数：10

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