Exercise-induced hemoconcentration in heart failure due to dilated cardiomyopathy

被引：20

作者：

Agostoni, P

Wasserman, K

Guazzi, M

Cattadori, G

Palermo, P

Marenzi, G

Guazzi, MD

机构：

[1] Univ Milan, Ist Cardiol, I-20138 Milan, Italy

[2] Univ Calif Los Angeles, Sch Med, Los Angeles Cty Harbor Med Ctr, Dept Med,Div Resp & Crit Care Med, Torrance, CA 90509 USA

[3] IRCCS, Ctr Cardiol, Ffn Manzino, Milan, Italy

[4] CNR, Ctr Studio Ric Cardiovasc, I-20133 Milan, Italy

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1999年 / 83卷 / 02期

关键词：

D O I：

10.1016/S0002-9149(98)00839-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Exercise-induced hemoconcetration is a useful mechanism, particularly in heart failure, because it increases oxygen content of blood, perfusing the working muscles; in 50 normal subjects and 50 patients with congestive heart failure, hemoglobin at peak exercise increased by 7 +/- 3% and 5 +/- 3%, respectively. Hemoconcentration was due to fluid flux out of the vascular bed, likely through oncotic forces related to intracellular lactate accumulation and not to red blood cell recruitment from other organs (spleen), because hemoglobin increase, as a percentage, was similar to plasma protein increase.

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页码：278 / +

页数：4

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