Cerebral processing of auditory and noxious stimuli in severely brain injured patients: Differences between VS and MCS

被引：90

作者：

Boly, M ^{[1
]}

Faymonville, ME ^{[1
]}

Peigneux, P ^{[1
]}

Lambermont, B ^{[1
]}

Damas, F ^{[1
]}

Luxen, A ^{[1
]}

Lamy, M ^{[1
]}

Moonen, G ^{[1
]}

Maquet, P ^{[1
]}

Laureys, S ^{[1
]}

机构：

[1] Univ Liege, Cyclotron Res Ctr, B-4000 Liege, Belgium

来源：

NEUROPSYCHOLOGICAL REHABILITATION | 2005年 / 15卷 / 3-4期

关键词：

D O I：

10.1080/09602010443000371

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We review cerebral processing of auditory and noxious stimuli in minimally conscious state (MCS) and vegetative state (VS) patients. In contrast with limited brain activation found in VS patients, MCS patients show activation similar to controls in response to auditory, emotional and noxious stimuli. Despite an apparent clinical similarity between MCS and VS patients, functional imaging data show striking differences in cortical segregation and integration between these two conditions. However, in the absence of a generally accepted neural correlate of consciousness as measured by functional neuroirnaging, clinical assessment remains the gold standard for the evaluation and management of severely brain damaged patients.

引用

页码：283 / 289

页数：7

共 26 条

[1] Misdiagnosis of the vegetative state: Retrospective study in a rehabilitation unit [J].

Andrews, K ;

Murphy, L ;

Munday, R ;

Littlewood, C .

BRITISH MEDICAL JOURNAL, 1996, 313 (7048) :13-16

[2]

[Anonymous], HUMAN BRAIN FUNCTION

[3]

ASHWAL S, 1994, NEW ENGL J MED, V330, P1499

[4] Brain, conscious experience and the observing self [J].

Baars, BJ ;

Ramsoy, TZ ;

Laureys, S .

TRENDS IN NEUROSCIENCES, 2003, 26 (12) :671-675

[5] Emotion processing in the minimally conscious state [J].

Bekinschtein, T ;

Niklison, J ;

Sigman, L ;

Manes, F ;

Leiguarda, R ;

Manes, F ;

Armony, J ;

Owen, A ;

Carpintiero, S ;

Olmos, L ;

Manes, F .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2004, 75 (05) :788-788

[6] Auditory processing in severely brain injured patients - Differences between the minimally conscious state and the persistent vegetative state [J].

Boly, M ;

Faymonville, ME ;

Peigneux, P ;

Lambermont, B ;

Damas, P ;

Del Fiore, G ;

Degueldre, C ;

Franck, G ;

Luxen, A ;

Lamy, M ;

Moonen, G ;

Maquet, P ;

Laureys, S .

ARCHIVES OF NEUROLOGY, 2004, 61 (02) :233-238

[7]

CELESIA, 1993, ANN NEUROL, V33, P386

[8] ACCURACY OF DIAGNOSIS OF PERSISTENT VEGETATIVE STATE [J].

CHILDS, NL ;

MERCER, WN ;

CHILDS, HW .

NEUROLOGY, 1993, 43 (08) :1465-1467

[9] Psychophysiological and modulatory interactions in neuroimaging [J].

Friston, KJ ;

Buechel, C ;

Fink, GR ;

Morris, J ;

Rolls, E ;

Dolan, RJ .

NEUROIMAGE, 1997, 6 (03) :218-229

[10] The minimally conscious state - Definition and diagnostic criteria [J].

Giacino, JT ;

Ashwal, S ;

Childs, N ;

Cranford, R ;

Jennett, B ;

Katz, DI ;

Kelly, JP ;

Rosenberg, JH ;

Whyte, J ;

Zafonte, RD ;

Zasler, ND .

NEUROLOGY, 2002, 58 (03) :349-353

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