Manganese intoxication during total parenteral nutrition: report of two cases and review of the literature

被引：101

作者：

Nagatomo, S

Umehara, F

Hanada, K

Nobuhara, Y

Takenaga, S

Arimura, K

Osame, M

机构：

[1] Kagoshima Univ, Sch Med, Dept Internal Med 3, Kagoshima 890, Japan

[2] Imakiire Gen Hosp, Dept Neurol, Kagoshima, Japan

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 1999年 / 162卷 / 01期

关键词：

manganese intoxication; total parenteral nutrition; trace element; MRI; parkinsonism;

D O I：

10.1016/S0022-510X(98)00289-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report two cases of manganese (Mn) intoxication during total parenteral nutrition including manganese (Mn). Both patients showed parkinsonism with psychiatric symptoms and elevated serum Mn levels. Tl-weighted magnetic resonance images (MRI) revealed symmetrical high intensity lesions in the globus pallidus. Discontinuation of Mn supplementation and levodopa treatment improved the symptoms and MRI abnormalities in the both patients. Thus, careful attention should be paid to the long-term intravenous administration of Mn. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：102 / 105

页数：4

共 12 条

[1] Neurologic disorders due to brain manganese deposition in a jaundiced patient receiving long-term parenteral nutrition [J].