Zinc fingers hit off target

被引：7

作者：

Cheng, Linzhao ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Stem Cell Program, Inst Cell Engn, Baltimore, MD 21218 USA

来源：

NATURE MEDICINE | 2011年 / 17卷 / 10期

关键词：

NUCLEASES; GENOME; CELLS;

D O I：

10.1038/nm1011-1192

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1192 / 1193

页数：2

共 8 条

[1] Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project [J].

Birney, Ewan ;

Stamatoyannopoulos, John A. ;

Dutta, Anindya ;

Guigo, Roderic ;

Gingeras, Thomas R. ;

Margulies, Elliott H. ;

Weng, Zhiping ;

Snyder, Michael ;

Dermitzakis, Emmanouil T. ;

Stamatoyannopoulos, John A. ;

Thurman, Robert E. ;

Kuehn, Michael S. ;

Taylor, Christopher M. ;

Neph, Shane ;

Koch, Christoph M. ;

Asthana, Saurabh ;

Malhotra, Ankit ;

Adzhubei, Ivan ;

Greenbaum, Jason A. ;

Andrews, Robert M. ;

Flicek, Paul ;

Boyle, Patrick J. ;

Cao, Hua ;

Carter, Nigel P. ;

Clelland, Gayle K. ;

Davis, Sean ;

Day, Nathan ;

Dhami, Pawandeep ;

Dillon, Shane C. ;

Dorschner, Michael O. ;

Fiegler, Heike ;

Giresi, Paul G. ;

Goldy, Jeff ;

Hawrylycz, Michael ;

Haydock, Andrew ;

Humbert, Richard ;

James, Keith D. ;

Johnson, Brett E. ;

Johnson, Ericka M. ;

Frum, Tristan T. ;

Rosenzweig, Elizabeth R. ;

Karnani, Neerja ;

Lee, Kirsten ;

Lefebvre, Gregory C. ;

Navas, Patrick A. ;

Neri, Fidencio ;

Parker, Stephen C. J. ;

Sabo, Peter J. ;

Sandstrom, Richard ;

Shafer, Anthony .

NATURE, 2007, 447 (7146) :799-816

[2] An unbiased genome-wide analysis of zinc-finger nuclease specificity [J].

Gabriel, Richard ;

Lombardo, Angelo ;

Arens, Anne ;

Miller, Jeffrey C. ;

Genovese, Pietro ;

Kaeppel, Christine ;

Nowrouzi, Ali ;

Bartholomae, Cynthia C. ;

Wang, Jianbin ;

Friedman, Geoffrey ;

Holmes, Michael C. ;

Gregory, Philip D. ;

Glimm, Hanno ;

Schmidt, Manfred ;

Naldini, Luigi ;

von Kalle, Christof .

NATURE BIOTECHNOLOGY, 2011, 29 (09) :816-U72

[3] Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases [J].

Hockemeyer, Dirk ;

Soldner, Frank ;

Beard, Caroline ;

Gao, Qing ;

Mitalipova, Maisam ;

DeKelver, Russell C. ;

Katibah, George E. ;

Amora, Ranier ;

Boydston, Elizabeth A. ;

Zeitler, Bryan ;

Meng, Xiangdong ;

Miller, Jeffrey C. ;

Zhang, Lei ;

Rebar, Edward J. ;

Gregory, Philip D. ;

Urnov, Fyodor D. ;

Jaenisch, Rudolf .

NATURE BIOTECHNOLOGY, 2009, 27 (09) :851-U110

[4] In vivo genome editing restores haemostasis in a mouse model of haemophilia [J].

Li, Hojun ;

Haurigot, Virginia ;

Doyon, Yannick ;

Li, Tianjian ;

Wong, Sunnie Y. ;

Bhagwat, Anand S. ;

Malani, Nirav ;

Anguela, Xavier M. ;

Sharma, Rajiv ;

Ivanciu, Lacramiora ;

Murphy, Samuel L. ;

Finn, Jonathan D. ;

Khazi, Fayaz R. ;

Zhou, Shangzhen ;

Paschon, David E. ;

Rebar, Edward J. ;

Bushman, Frederic D. ;

Gregory, Philip D. ;

Holmes, Michael C. ;

High, Katherine A. .

NATURE, 2011, 475 (7355) :217-U128

[5] Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection [J].

Pattanayak, Vikram ;

Ramirez, Cherie L. ;

Joung, J. Keith ;

Liu, David R. .

NATURE METHODS, 2011, 8 (09) :765-U115

[6] Chimeric nucleases stimulate gene targeting in human cells [J].

Porteus, MH ;

Baltimore, D .

SCIENCE, 2003, 300 (5620) :763-763

[7] Attenuation of Zinc Finger Nuclease Toxicity by Small-Molecule Regulation of Protein Levels [J].

Pruett-Miller, Shondra M. ;

Reading, David W. ;

Porter, Shaina N. ;

Porteus, Matthew H. .

PLOS GENETICS, 2009, 5 (02)

[8] Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting [J].

Zou, Jizhong ;

Sweeney, Colin L. ;

Chou, Bin-Kuan ;

Choi, Uimook ;

Pan, Jason ;

Wang, Hongmei ;

Dowey, Sarah N. ;

Cheng, Linzhao ;

Malech, Harry L. .

BLOOD, 2011, 117 (21) :5561-5572

← 1 →