Cervical disc degeneration and neck pain

被引:120
作者
Peng, Baogan [1 ]
DePalma, Michael J. [2 ]
机构
[1] Armed Police Force, Gen Hosp, Dept Spinal Surg, Beijing 100039, Peoples R China
[2] Virginia Spine Res Inst Inc, Virginia iSpine Phys PC, Intervent Spine & Musculoskeletal Care, Richmond, VA USA
关键词
cervical intervertebral disc; chronic neck pain; discogenic neck pain; disc degeneration; anterior cervical surgery; cervical discography; INTERVERTEBRAL DISC; TNF-ALPHA; DISCOGRAPHY; FUSION; INNERVATION; DISKECTOMY; MANAGEMENT; DIAGNOSIS;
D O I
10.2147/JPR.S180018
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Cervical intervertebral disc has long been considered a common source of neck pain. However, the pain caused by the disc itself has not been clearly defined so far, and its diagnosis and treatment has always been controversial. Degenerative cervical disc has a rich supply of nerve fibers, is prone to inflammatory reactions, and is susceptible to pain that can be provoked by disc stimulation or distention, and can be eliminated by block. Overwhelming clinical evidence demonstrates that neck pain in patients with degenerative cervical radiculopathy or myelopathy can be subsided rapidly by anterior cervical surgery, further indicating that this neck pain stems from the pathology of cervical disc itself. Cervical discography is advocated as the only test that connects disease to symptoms, but the procedure remains controversial. If strict criteria and technique are maintained, discography can discriminate painful, symptomatic discs from nonpainful, asymptomatic discs. Discogenic neck pain alone without cervical disc herniation or cervical spondylosis accounts for a large proportion of chronic neck pain. For these patients who continue to have refractory neck pain and fail to respond to conservative treatment, anterior cervical fusion surgery or artificial cervical disc replacement may be a better choice, and preoperative cervical discography can guarantee the excellent surgical results. Existing basic and clinical studies have scientifically shown that cervical intervertebral disc degeneration can lead to neck pain.
引用
收藏
页码:2853 / 2857
页数:5
相关论文
共 32 条
[1]
Cervical spondylosis and neck pain [J].
Binder, Allan I. .
BMJ-BRITISH MEDICAL JOURNAL, 2007, 334 (7592) :527-531
[2]
THE INNERVATION OF THE CERVICAL INTERVERTEBRAL DISKS [J].
BOGDUK, N ;
WINDSOR, M ;
INGLIS, A .
SPINE, 1988, 13 (01) :2-8
[3]
TREATMENT OF NECK PAIN Injections and Surgical Interventions: Results of the Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders (Reprinted from Spine, vol 33, pg S153-S169, 2008) [J].
Carragee, Eugene J. ;
Hurwitz, Eric L. ;
Cheng, Ivan ;
Carroll, Linda J. ;
Nordin, Margareta ;
Guzman, Jaime ;
Peloso, Paul ;
Holm, Lena W. ;
Cote, Pierre ;
Hogg-Johnson, Sheilah ;
van der Velde, Gabrielle ;
Cassidy, J. David ;
Haldeman, Scott .
JOURNAL OF MANIPULATIVE AND PHYSIOLOGICAL THERAPEUTICS, 2009, 32 (02) :S176-S193
[4]
Artificial Cervical Disc Arthroplasty A Systematic Review [J].
Cepoiu-Martin, Monica ;
Faris, Peter ;
Lorenzetti, Diane ;
Prefontaine, Eliza ;
Noseworthy, Tom ;
Sutherland, Lloyd .
SPINE, 2011, 36 (25) :E1623-E1633
[5]
CLOWARD RB, 1958, AMER J ROENTGENOL RA, V79, P563
[6]
Advances in the diagnosis and management of neck pain [J].
Cohen, Steven P. ;
Hooten, W. Michael .
BMJ-BRITISH MEDICAL JOURNAL, 2017, 358
[7]
Identifying and Treating the Causes of Neck Pain [J].
Evans, Ginger .
MEDICAL CLINICS OF NORTH AMERICA, 2014, 98 (03) :645-+
[8]
The prevalence of neck pain in the world population: a systematic critical review of the literature [J].
Fejer, Rene ;
Kyvik, Kirsten Ohm ;
Hartvigsen, Jan .
EUROPEAN SPINE JOURNAL, 2006, 15 (06) :834-848
[9]
FERLIC DC, 1963, B JOHNS HOPKINS HOSP, V113, P347
[10]
Sensory and Autonomic Innervation of the Cervical Intervertebral Disc in Rats The Pathomechanics of Chronic Discogenic Neck Pain [J].
Fujimoto, Kazuki ;
Miyagi, Masayuki ;
Ishikawa, Tetsuhiro ;
Inoue, Gen ;
Eguchi, Yawara ;
Kamoda, Hiroto ;
Arai, Gen ;
Suzuki, Miyako ;
Orita, Sumihisa ;
Kubota, Gou ;
Sakuma, Yoshihiro ;
Oikawa, Yasuhiro ;
Kuniyoshi, Kazuki ;
Ochiai, Nobuyasu ;
Kishida, Shunji ;
Nakamura, Junichi ;
Aoki, Yasuchika ;
Toyone, Tomoaki ;
Takahashi, Kazuhisa ;
Ohtori, Seiji .
SPINE, 2012, 37 (16) :1357-1362