Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group

被引:444
作者
Lambert, Robert G. W. [1 ]
Bakker, Pauline A. C. [2 ]
van der Heijde, Desiree [2 ]
Weber, Ulrich [3 ,4 ,5 ]
Rudwaleit, Martin [6 ,7 ]
Hermann, Kay-Geert A. [8 ]
Sieper, Joachim [7 ]
Baraliakos, Xenofon [9 ]
Bennett, Alex [10 ]
Braun, Jurgen [9 ]
Burgos-Vargas, Ruben [11 ,12 ]
Dougados, Maxime [13 ]
Pedersen, Susanne Juhl [14 ,15 ]
Jurik, Anne Grethe [16 ]
Maksymowych, Walter P. [17 ]
Marzo-Ortega, Helena [18 ,19 ]
Ostergaard, Mikkel [14 ,15 ]
Poddubnyy, Denis [7 ]
Reijnierse, Monique [20 ]
van den Bosch, Filip [21 ]
van der Horst-Bruinsma, Irene [22 ]
Landewe, Robert [23 ]
机构
[1] Univ Alberta, Dept Radiol & Diagnost Imaging, 2A2-41 WMC,8440-112 St, Edmonton, AB T6G 2B7, Canada
[2] Leiden Univ, Med Ctr, Dept Rheumatol, Leiden, Netherlands
[3] King Christian 10th Hosp Rheumat Dis, Grasten, Denmark
[4] Univ Southern Denmark, South Jutland Hosp, Odense, Denmark
[5] Univ Southern Denmark, Inst Reg Hlth Serv Res, Odense, Denmark
[6] Endokrinologikum Berlin, Berlin, Germany
[7] Charite, Berlin, Germany
[8] Charite, Dept Radiol, Berlin, Germany
[9] Ruhr Univ Bochum, Rheumazentrum Ruhrgebiet Herne, Herne, Germany
[10] Def Med Rehabil Ctr, Surry, England
[11] Hosp Gen Mexico City, Dept Rheumatol, Mexico City, DF, Mexico
[12] Univ Nacl Autonoma Mexico, Fac Med, Mexico City, DF, Mexico
[13] Paris Descartes Univ, Hop Cochin, PRES Sorbonne Paris Cite, Clin Epidemiol & Biostat,Dept Rheumatol, Paris, France
[14] Rigshosp, Ctr Rheumatol & Spine Dis, Copenhagen Ctr Arthrit Res, Glostrup, Denmark
[15] Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark
[16] Aarhus Univ Hosp, Dept Radiol, Aarhus, Denmark
[17] Univ Alberta, Dept Med, Edmonton, AB, Canada
[18] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds, W Yorkshire, England
[19] Leeds Teaching Hosp NHS Trust, NIHR Leeds Musculoskeletal Biomed Res Unit, Leeds, W Yorkshire, England
[20] Leiden Univ, Med Ctr, Dept Radiol, Leiden, Netherlands
[21] Ghent Univ Hosp, Ghent, Belgium
[22] Vrije Univ Amsterdam, Med Ctr, Dept Rheumatol, Amsterdam, Netherlands
[23] Acad Med Ctr, Amsterdam Rheumatol & Immunol Ctr, Amsterdam, Netherlands
关键词
INFLAMMATORY BACK-PAIN; ANKYLOSING-SPONDYLITIS; SPACE COHORT; DESIR COHORT; JOINTS; GADOLINIUM; SPONDYLARTHRITIS; RADIOLOGISTS; CRITERIA;
D O I
10.1136/annrheumdis-2015-208642
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Objectives To review and update the existing definition of a positive MRI for classification of axial spondyloarthritis (SpA). Methods The Assessment in SpondyloArthritis International Society (ASAS) MRI working group conducted a consensus exercise to review the definition of a positive MRI for inclusion in the ASAS classification criteria of axial SpA. Existing definitions and new data relevant to the MRI diagnosis and classification of sacroiliitis and spondylitis in axial SpA, published since the ASAS definition first appeared in print in 2009, were reviewed and discussed. The precise wording of the existing definition was examined in detail and the data and a draft proposal were presented to and voted on by the ASAS membership. Results The clear presence of bone marrow oedema on MRI in subchondral bone is still considered to be the defining observation that determines the presence of active sacroiliitis. Structural damage lesions seen on MRI may contribute to a decision by the observer that inflammatory lesions are genuinely due to SpA but are not required to meet the definition. The existing definition was clarified adding guidelines and images to assist in the application of the definition. Conclusion The definition of a positive MRI for classification of axial SpA should continue to primarily depend on the imaging features of 'active sacroiliitis' until more data are available regarding MRI features of structural damage in the sacroiliac joint and MRI features in the spine and their utility when used for classification purposes.
引用
收藏
页码:1958 / 1963
页数:6
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