Radiopharmaceuticals in sentinel lymph-node detection - an overview

被引：137

作者：

Wilhelm, AJ

Mijnhout, GS

Franssen, EJF

机构：

[1] Vrije Univ Amsterdam, Acad Ziekenhuis, Dept Hosp Pharm, NL-1007 MB Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Acad Ziekenhuis, Dept Nucl Med, NL-1007 MB Amsterdam, Netherlands

来源：

EUROPEAN JOURNAL OF NUCLEAR MEDICINE | 1999年 / 26卷 / 04期

关键词：

sentinel node; Tc-99m-sulfur colloid; Tc-99m-antimony trisulfide colloid; Tc-99m-colloidal albumin; radiocolloids;

D O I：

10.1007/s002590050576

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Biopsy of the first tumour-draining lymph node (sentinel node, SN) is bound to become the procedure of choice in regional staging of melanoma and breast cancer patients. Several radiopharmaceuticals have been developed for lymphoscintigraphy. In this paper we review the most frequently used radiopharmaceuticals for their appropriateness in the sentinel-node procedure. We conclude that accurate localization of SNs is demonstrated using technetium-99m-sulfur colloid (Tc-99m-SC), Tc-99m antimony trisulfide colloid (Tc-99m-ATC) [10] and Tc-99m nanocolloidal albumin (Tc-99m-CA). Tc-99m-Ca and Tc-99m-SC are both available in Europe. In the United States Tc-99m-SC is the only registered tracer for lymphoscintigraphy.

引用

页码：S36 / S42

页数：7

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