Imidazole alkaloids from Lepidium meyenii

被引：196

作者：

Cui, BL ^{[1
]}

Zheng, BL ^{[1
]}

He, K ^{[1
]}

Zheng, QY ^{[1
]}

机构：

[1] PureWorld Bot Inc, S Hackensack, NJ 07606 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2003年 / 66卷 / 08期

关键词：

D O I：

10.1021/np030031i

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new imidazole alkaloids (lepidiline A and lepidiline B) have been isolated from a root extract of Lepidium meyenii with the common name Maca and identified as 1,3-dibenzyl-4,5-dimethylimidazolium chloride (1) and 1,3-dibenzyl-2,4,5-trimethylimidazolium chloride (2), respectively. The structures of these two new compounds were determined by spectroscopic methods, as well as single-crystal X-ray diffraction performed on compound 1.

引用

页码：1101 / 1103

页数：3

共 9 条

[1]

COOKS RG, 1968, J CHEM SOC C, V23, P2864

[2] CHEMICAL-COMPOSITION OF LEPIDIUM-MEYENII [J].

DINI, A ;

MIGLIUOLO, G ;

RASTRELLI, L ;

SATURNINO, P ;

SCHETTINO, O .

FOOD CHEMISTRY, 1994, 49 (04) :347-349

[3] Synthesis, acidity and F-19 NMR characteristics of imidazoles bearing 1-fluorinated substituents with potential application as probes for intracellular pH determination. [J].

Harper, JL ;

Smith, RAJ ;

Bedford, JJ ;

Leader, JP .

TETRAHEDRON, 1997, 53 (24) :8211-8224

[4]

Johns T., 1981, J ETHNOBIOL, V1, P208

[5]

LEON J., 1964, Economic Botany, V18, P122, DOI 10.1007/BF02862707

[6]

MAIN P, 1982, 1182 MULTAN U YORK U

[7] Constituents of Lepidium meyenii 'maca' [J].

Muhammad, I ;

Zhao, JP ;

Dunbar, DC ;

Khan, IA .

PHYTOCHEMISTRY, 2002, 59 (01) :105-110

[8]

Zheng B. L., 2001, U.S. Patent, Patent No. [6,267,995,, 6267995]

[9] Effect of a lipidic extract from Lepidium meyenii on sexual behavior in mice and rats [J].

Zheng, BL ;

He, K ;

Kim, CH ;

Rogers, L ;

Shao, Y ;

Huang, ZY ;

Lu, Y ;

Yan, SJ ;

Qien, LC ;

Zheng, QY .

UROLOGY, 2000, 55 (04) :598-602

← 1 →