Water-soluble green perylenediimide (PDI) dyes as potential sensitizers for photodynamic therapy

被引：142

作者：

Yukruk, F ^{[1
]}

Dogan, AL

Canpinar, H

Guc, D

Akkaya, EU

机构：

[1] Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey

[2] Hacettepe Univ, Inst Oncol, Dept Basic Oncol, TR-06100 Ankara, Turkey

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 14期

关键词：

D O I：

10.1021/ol050841g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of water-soluble green perylenediimide (PDI) dyes have been synthesized. On red light excitation, these dyes were shown to be efficient generators of singlet oxygen, and in cell culture media, they were shown to display significant light-induced cytotoxic effects on the human erythroleukemia cell line (K-562). It appears that highly versatile PDI dyes are likely to find new applications in photodynamic therapy.

引用

页码：2885 / 2887

页数：3

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