Spiro-prorocentrimine, a novel macrocyclic lactone from a benthic Prorocentrum sp of Taiwan

被引：71

作者：

Lu, CK

Lee, GH

Huang, R

Chou, HN ^{[1
]}

机构：

[1] Natl Taiwan Univ, Inst Oceanog, Taipei 10671, Taiwan

[2] Natl Taiwan Univ, Coll Sci, Instrument Ctr, Taipei 10671, Taiwan

[3] Natl Taiwan Univ, Inst Fisheries Sci, Taipei 10671, Taiwan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 09期

关键词：

Prorocentrum; marine toxin; spiro-prorocentrimine; X-ray crystallography;

D O I：

10.1016/S0040-4039(00)02331-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Spiro-prorocentrimine, C42H69NO13S, is a polar lipid-soluble toxin isolated from a laboratory-cultured benthic Prorocentrum species of Taiwan, crystallized in methanol. X-ray diffraction analysis of the compound revealed a spiro-linked cyclic imine with the ortho, para-disubstituted 3'-cyclohexene in addition to its macrolide skeleton. C-13 and H-1 NMR signals were then assigned accordingly. This is the first compound of this group of marine toxins with a clear stereochemistry. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：1713 / 1716

页数：4

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