Ruthenium-catalyzed arylation of 2-alkenylpyridines with aryl bromides:: Alternative E,Z-selectivity to Mizoroki-Heck reaction

被引：104

作者：

Oi, S ^{[1
]}

Sakai, K ^{[1
]}

Inoue, Y ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Engn, Dept Biomol Engn, Sendai, Miyagi 9808579, Japan

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 18期

关键词：

D O I：

10.1021/ol051654l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[Graphics] Regio- and stereoselective arylation of 2-alkenylpyridines with aryl bromides is catalyzed by specific Ru(II)-phosphine complexes affording beta-arylated (Z)-2-alkenylpyridines, in which the aryl moiety is introduced cis to the pyridyl group. This geometrical selectivity is in sharp contrast to the Mizoroki-Heck reaction.

引用

页码：4009 / 4011

页数：3

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