A histone code for chromatin assembly

被引:21
作者
Fillingham, Jeffrey [1 ]
Greenblatt, Jack F. [1 ]
机构
[1] Univ Toronto, Terrence Donnelly Ctr Cellular & Biomol Res CCBR, Banting & Best Dept Med Res, Toronto, ON M5S 3E1, Canada
关键词
D O I
10.1016/j.cell.2008.07.007
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue, two papers implicate histone H3 lysine 56 acetylation in histone deposition in chromatin. Li et al. ( 2008) show that acetylation of H3K56 promotes S phase chromatin assembly that is mediated by the histone chaperones CAF-1 and Rtt106. Chen et al. ( 2008) establish that the acetylation mark promotes chromatin reassembly following DNA double-strand break repair.
引用
收藏
页码:206 / 208
页数:5
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