The α-(1→6) glycosidic linkage as a novel conformational entropic regulator in osmoregulated periplasmic α-cyclosophorohexadecaose

被引：5

作者：

Choi, Y

Jung, SH

机构：

[1] Konkuk Univ, Biomol Informat Ctr, Dept Microbial Engn, Seoul 143701, South Korea

[2] Konkuk Univ, Biomol Informat Ctr, Dept Adv Technol Fus, Seoul 143701, South Korea

来源：

CARBOHYDRATE RESEARCH | 2005年 / 340卷 / 16期

关键词：

biological water; conformational entropy; glycosidic linkage; molecular dynamics; cyclic osmoregulated periplasmic glucan;

D O I：

10.1016/j.carres.2005.08.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Molecular dynamics simulations were performed to explain the conformational effect of an alpha-(1-->6)-glycosidic linkage upon the cyclic osmoregulated periplasmic glucan (OPG) produced by Xanthomonas campestris pv. citri. We suggest that a single alpha-(1-->6)-glycosidic linkage in cyclic OPG functions as a novel entropic regulator, which reduces the conformational entropy of cyclic OPG and increases the motional entropy of solvent water molecules. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：2550 / 2557

页数：8

共 32 条

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