Good adhesion properties of probiotics: a potential risk for bacteremia?

被引:54
作者
Apostolou, E
Kirjavainen, PV
Saxelin, M
Rautelin, H
Valtonen, V
Salminen, SJ
Ouwehand, AC [1 ]
机构
[1] Univ Turku, Dept Biochem & Food Chem, FIN-20014 Turku, Finland
[2] Valio Ltd, Helsinki, Finland
[3] Univ Helsinki, Dept Bacteriol & Immunol, Helsinki, Finland
[4] Univ Helsinki, Cent Hosp Lab Diagnost, Helsinki, Finland
[5] Univ Helsinki, Cent Hosp, Dept Infect Dis, Helsinki, Finland
来源
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2001年 / 31卷 / 01期
关键词
mucus; adhesion; lactic acid bacterium; safety; probiotic; Lactobacillus bacteremia;
D O I
10.1111/j.1574-695X.2001.tb01583.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The ability to adhere to human intestinal mucus was tested for lactic acid bacteria of clinical blood culture, human fecal and dairy origin. The blood culture isolates were found to adhere better than the dairy strains. Of the Lactobacillus rhamnosus strains (nine clinical, 10 fecal and three dairy), blood culture isolates adhered better than the fecal strains. Although these results indicate a trend for blood culture isolates to bind to intestinal mucus in higher numbers than strains of dairy and human fecal origin, other factors are also likely to be involved in the etiology of lactobacillemia since some of the clinical Lactobacillus isolates exhibited a relatively low level of adhesion. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:35 / 39
页数:5
相关论文
共 17 条
[1]   LACTIC-ACID BACTERIA AND HUMAN CLINICAL INFECTION [J].
AGUIRRE, M ;
COLLINS, MD .
JOURNAL OF APPLIED BACTERIOLOGY, 1993, 75 (02) :95-107
[2]  
Antony Suresh J., 2000, Journal of the National Medical Association, V92, P83
[3]  
COHEN PS, 1995, METHOD ENZYMOL, V253, P309
[4]   Common themes in microbial pathogenicity revisited [J].
Finlay, BB ;
Falkow, S .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1997, 61 (02) :136-+
[5]   Lactobacillus species as emerging pathogens in neutropenic patients [J].
Fruchart, C ;
Salah, A ;
Gray, C ;
Martin, E ;
Stamatoullas, A ;
Bonmarchand, G ;
Lemeland, JF ;
Tilly, H .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1997, 16 (09) :681-684
[6]   PATHOGENIC POTENTIAL OF LACTOBACILLI [J].
HARTY, DWS ;
OAKEY, HJ ;
PATRIKAKIS, M ;
HUME, EBH ;
KNOX, KW .
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 1994, 24 (1-2) :179-189
[7]  
HENRIKSSON A, 1995, FEMS MICROBIOL ECOL, V16, P55, DOI 10.1111/j.1574-6941.1995.tb00268.x
[8]   Lactobacillus bacteremia and endocarditis: Review of 45 cases [J].
Husni, RN ;
Gordon, SM ;
Washington, JA ;
Longworth, DL .
CLINICAL INFECTIOUS DISEASES, 1997, 25 (05) :1048-1055
[9]   In vitro adhesion and platelet aggregation properties of bacteremia-associated lactobacilli [J].
Kirjavainen, PV ;
Tuomola, EM ;
Crittenden, RG ;
Ouwehand, AC ;
Harty, DWS ;
Morris, LF ;
Rautelin, H ;
Playne, MJ ;
Donohue, DC ;
Salminen, SJ .
INFECTION AND IMMUNITY, 1999, 67 (05) :2653-2655
[10]  
Kirjavainen PV, 1998, FEMS MICROBIOL LETT, V167, P185, DOI 10.1111/j.1574-6968.1998.tb13226.x