Amyloid-β: redox-metal chelator and antioxidant

被引：23

作者：

Atwood, C. S. ^{[1
]}

Robinson, S. R. ^{[2
]}

Smith, M. A. ^{[1
]}

机构：

[1] Case Western Reserve Univ, Inst Pathol, 2085 Adelbert Rd, Cleveland, OH 44106 USA

[2] Monash Univ, Dept Psychol, Clayton, Vic 3800, Australia

来源：

JOURNAL OF ALZHEIMERS DISEASE | 2002年 / 4卷 / 03期

关键词：

Alzheimer's disease; A beta; A beta PP expression; acute phase response; metal ions; glutamine synthetase; iron; copper; oxidation; oxidative stress; injury; head trauma; chelation; neurotrophic; neurotoxic;

D O I：

10.3233/JAD-2002-4310

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

[No abstract available]

引用

页码：203 / 214

页数：12

共 138 条

[1] INDUCTION OF AMYLOID PRECURSOR PROTEIN MESSENGER-RNA AFTER HEAT-SHOCK IN CULTURED HUMAN LYMPHOBLASTOID-CELLS [J].

ABE, K ;

STGEORGEHYSLOP, PH ;

TANZI, RE ;

KOGURE, K .

NEUROSCIENCE LETTERS, 1991, 125 (02) :169-171

[2] Oxidative modification of glutamine synthetase by amyloid beta peptide [J].

Aksenov, MY ;

Aksenova, MV ;

Carney, JM ;

Butterfield, DA .

FREE RADICAL RESEARCH, 1997, 27 (03) :267-281

[3]

Andorn Anne C., 2000, Journal of Alzheimer's Disease, V2, P69

[4]

[Anonymous], GLIAL CELLS THEIR RO

[5] RELEASE OF ENDOGENOUS ZN-2+ FROM BRAIN-TISSUE DURING ACTIVITY [J].

ASSAF, SY ;

CHUNG, SH .

NATURE, 1984, 308 (5961) :734-736

[6] Dramatic aggregation of Alzheimer Aβ by Cu(II) is induced by conditions representing physiological acidosis [J].

Atwood, CS ;

Moir, RD ;

Huang, XD ;

Scarpa, RC ;

Bacarra, NME ;

Romano, DM ;

Hartshorn, MK ;

Tanzi, RE ;

Bush, AI .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (21) :12817-12826

[7] Characterization of copper interactions with Alzheimer amyloid β peptides:: Identification of an attomolar-affinity copper binding site on amyloid β1-42 [J].

Atwood, CS ;

Scarpa, RC ;

Huang, XD ;

Moir, RD ;

Jones, WD ;

Fairlie, DP ;

Tanzi, RE ;

Bush, AI .

JOURNAL OF NEUROCHEMISTRY, 2000, 75 (03) :1219-1233

[8]

Atwood CS, 1999, MET IONS BIOL SYST, V36, P309

[9] Neuroinflammatory responses in the Alzheimer's disease brain promote the oxidative post-translational modification of amyloid deposits [J].

Atwood, CS ;

Huang, XD ;

Moir, RD ;

Smith, MA ;

Tanzi, RE ;

Roher, AE ;

Bush, AI ;

Perry, G .

ALZHEIMER'S DISEASE: ADVANCES IN ETIOLOGY, PATHOGENESIS AND THERAPEUTICS, 2001, :341-361

[10] EVIDENCE THAT COPPER AMINO-ACID COMPLEXES ARE POTENT STIMULATORS OF THE RELEASE OF LUTEINIZING-HORMONE-RELEASING HORMONE FROM ISOLATED HYPOTHALAMIC GRANULES [J].

BARNEA, A ;

CHO, G .

ENDOCRINOLOGY, 1984, 115 (03) :936-943

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