Handedness and hemispheric language dominance in healthy humans

被引：1058

作者：

Knecht, S ^{[1
]}

Dräger, B ^{[1
]}

Deppe, M ^{[1
]}

Bobe, L ^{[1
]}

Lohmann, H ^{[1
]}

Flöel, A ^{[1
]}

Ringelstein, EB ^{[1
]}

Henningsen, H ^{[1
]}

机构：

[1] Univ Munster, Dept Neurol, D-48129 Munster, Germany

来源：

BRAIN | 2000年 / 123卷

关键词：

language lateralization; hemispheric dominance; handedness; functional Doppler ultrasonography;

D O I：

10.1093/brain/123.12.2512

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In most people the left hemisphere of the brain is dominant for language. Because of the increased incidence of atypical right-hemispheric language in left-handed neurological patients, a systematic association between handedness and dominance has long been suspected. To clarify the relationship between handedness and language dominance in healthy subjects, we measured lateralization directly by functional transcranial Doppler sonography in 326 healthy individuals using a word-generation task. The incidence of right-hemisphere language dominance was found to increase linearly with the degree of left-handedness, from 4% in strong right-handers (handedness = 100) to 15% in ambidextrous individuals and 27% in strong left-handers (handedness = -100), The relationship could be approximated by the formula: likelihood of right-hemisphere language dominance (%) = 15% handedness (%)/10. These results clearly demonstrate that the relationship between handedness and language dominance is not an artefact of cerebral pathology but a natural phenomenon.

引用

页码：2512 / 2518

页数：7

共 31 条

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