Supercritical fluid mixing: preparation of thermally sensitive polymer composites containing bioactive materials

被引：198

作者：

Howdle, SM ^{[1
]}

Watson, MS

Whitaker, MJ

Popov, VK

Davies, MC

Mandel, FS

Wang, JD

Shakesheff, KM

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

[2] Univ Nottingham, Sch Pharmaceut Sci, Nottingham NG7 2RD, England

[3] Russian Acad Sci, Inst Laser & Informat Technol, LaserChem Grp, Troitsk 142092, Russia

[4] Ferro Corp, Independence, OH 44131 USA

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 01期

关键词：

D O I：

10.1039/b008188o

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the use of supercritical carbon dioxide (scCO(2)) to create a diverse range of polymeric composites incorporating thermal and solvent labile guest materials such as proteins; no additional co-solvents are required; the entire process can be carried out at near ambient conditions; polymer morphology is controllable; high loadings of guest species can be achieved and the protein function is retained.

引用

页码：109 / 110

页数：2

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