Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy

被引：12

作者：

Chen, KC ^{[1
]}

Yang, YK ^{[1
]}

Chen, PS ^{[1
]}

Yeh, TL ^{[1
]}

Yang, MJ ^{[1
]}

机构：

[1] Natl Cheng Kung Univ, Med Coll & Hosp, Dept Psychiat, Tainan 70101, Taiwan

来源：

PSYCHIATRY AND CLINICAL NEUROSCIENCES | 2003年 / 57卷 / 04期

关键词：

benzodiazepine; hypothermia; valproate; zotepine;

D O I：

10.1046/j.1440-1819.2003.01133.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate,and benzodiazepine. Two cases of hypothermia occurred after combining the use of zotepine, valproate, and benzodiazepine. The valproate was under therapeutic blood level when zotepine dosage was raised to 200 mg/day, and hypothermia occurred. The dosage of zotepine might constitute a positive correlation with hypothermia. The combination of zotepine, valproate or benzodiazepine may cause hypothermia as a side-effect.

引用

页码：369 / 371

页数：3

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